Гаджева В. Синтез, свойства и биологична активност на спин-белязани и небелязани нитрозоуреи и триазени. Дисертация за присъждане на научна степен “Доктор”, 1991 Гаджева В



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СПИСЪК

на научните трудове

на проф. Веселина Георгиева Гаджева, дхн

общ импакт фактор: 104.906




  1. Гаджева В. Синтез, свойства и биологична активност на спин-белязани и небелязани нитрозоуреи и триазени. Дисертация за присъждане на научна степен “Доктор”, 1991

  2. Гаджева В. Ефекти на спин-белязани съединения върху оксидативните токсични увреждания, причинени от противотуморни препарати, Дисертация за присъждане на научната степен “Доктор на химическите науки” , 2006



I.Научни статии в пълен текст


I.1. Научни статии, публикувани в международни списания

1993


  1. Raikov Z, V. Gadzheva, M. Koch and G. Kolar: Synthesis of spin-labeled triazenes.Org. Prep. Proc. Int. Briefs. 25(4), 473-477, 1993. (IF= 0.841)


1994

  1. Gadzheva V, K. Ichimory, H. Nakazawa and Z. Raikov: Superoxide scavenging activity of spin-labeled nitrosourea and triazene derivatives. Free Radical Research. 21(3), 177-186,1994. (IF= 2.743)

  2. Ichimory, K, Gadzheva V, H. Nakazawa, Z. Raikov: Superoxide scavenging activity of a sample containing an XOD inhibitor. Mag. Reson. Med. 5(3), 53-57, 1994 (in Japanese). (IF= 3.757)

1997

  1. Gadzheva V, K. Ichimory, Z. Raikov and H. Nakazawa: New Method to Measure the Carbamoylating Activity of Nitrosoureas by Electron Paramagnetic Resonance Spectroscopy. Free Radical Research. 27, 197-206, 1997. (IF=2.743)


1998

  1. Koldamova R., I. Lefterov, V. Gadjeva and J. Lazo J: Essential Binding and Functional Domains of Human Bleomycin Hydrolase. Biochemistry: 37, 2282-2290, 1998. (IF=5.234)


1999

  1. Gadjeva V. and Z. Raikov: Syntheses and antitumor activity of 4-{N-[N-(2-chloroethyl)-N-nitrosocarbamoyl]hydrazono}-2,2,6,6-tetramethylpiperidine-1-oxyl. Die Pharmazie, 54(13), 1999. (IF=0.504)

  2. Gadjeva V., A. Zheleva and E. Raikova: Modulating Effect of New Potential Antimelanomic Agents, Spin labeled Triazenes and Nitrosoureas on DOPA-oxidase Activity of Tyrosinase. Cancer Bioch. Bioph., 17(2), 1999. (IF= 0.585)


2000

  1. Ivanov I., Gadjeva V. Influence of some DNA-alkylating drugs on thermal stability, acid and osmotic resistance of the membrane of whole human erythrocytes and their ghosts.
    Die Pharmazie. 2000 Sep;55(9):672-7. (IF =0.504)


2001

  1. Zheleva А and Gadjeva V: Spin labeled nitrosoureas and triazenes and their nonlabeled clinically used analogues – a comparative study on their physicochemical properties and antimelanomic effects. Int J Pharmаceutics. 2001;212(2):257-266. (IF= 1.539)

  2. Hristozov D., V. Gadjeva, T. Vlaykova, S Popova, G. Dimitrov. Evaluation of Oxidative Stress in Patients with Cancer. Archives of Physiology and Biochemistry. 109 (4), 2001, 331-336. (IF- 0.479)

  3. V. Gadjeva and R. Koldamova. Spin-labeled 1-alkyl-1-nitrosourea synergists of antitumor antibiotics. Anticancer Drug Design 2001, 16(4-5):247-53. (IF- 2,339)


2002

  1. V.Gadjeva. Structure-based design of nitrosoureas containing tyrosine derivatives as potential antimelanoma agents. Eur. J. Med. Chemistry 2002, 37, 295-300. (IF= 1,681)

  2. V. Gadjeva. Two spin labeled triazenes: relationship between biochemical and biological activities. Int J Pharm. 2002, 247(1-2):39-45. (IF= 1.539)

  3. Georgieva N, Gadjeva V. Isonicotinoylhydrazone Analogs of Isoniazid: Relationship between Superoxide Scavenging and Tuberculostatic Activities.
    Biochemistry (Mosc). 2002 67(5):588-91. (IF = 1,17)


2003

  1. Gadjeva V, Lazarova G, Zheleva A. Spin labeled antioxidants protect bacteria against the toxicity of alkylating antitumor drug CCNU.
    Toxicol Lett. 2003 15;144(3): 289-94. (IF= 3,237)

  2. Tanchev S., V. Gadjeva, S.Stanilova. Influence of Antigen Stimulation on the Oxidative Stress Parameters in Autbred and Inbred Rabbits. Archives of Physiology and Biochemistry. 2003 Dec;111(5):437-42. (IF = 0,479)

  3. Popov, B., V. Gadjeva, P. Valkanov , S. Popova, A. Tolekova (2003). Lipid peroxidation, superoxide dismutase and catalase activities in brain tumor tissues. Arch. of Physiol. and Biochem. 111 (5) 455-459. (IF -0.479)

2004

  1. Simeonova, D., Todorova, G., Gadjeva, D. Dinev. (2004). Evaluation of lipid peroxidation associated with three anesthetic protocols in dogs. Revue de Medecine Veterinare 155, (12), 602 – 605. (IF= 0,148)


2005

  1. Georgieva, N. and V. Gadjeva, (2005). Beneficial effect of isonocotinoylhydrazones on isonoazid induced disruption of ecological oxidative balance. Medical Hypotheses 64 (3), 662. (IF = 0,684)

  2. Georgieva N., V. Gadjeva, A. Tolekova, D. Dimitrov, (2005). Hepatoprotective effect of isonicotinoylhydrazone SH7 against chronic isoniazid toxicity. Die Pharmazie 60, 138 - 141. (IF = 0, 696)

  3. Koinarski, V., N. Georgieva, V. Gadjeva, P. Petkov, (2005). Antioxidant status of broiler chickens, infected with Eimeria acervulina. Revue de Medecine Veterinare, 156 (10), 498-502. (IF= 0,148)

  4. Gadjeva V, Kuchukova D, Tolekova A, Tanchev S. (2005). Beneficial effects of spin-labelled nitrosourea on CCNU-induced oxidative stress in rat blood compared with vitamin E. Die Pharmazie 60: 530-532 (IF = 0, 696)

  5. Todorova, G. Simeonova, D. Kyuchukova, D. Dinev, V.Gadjeva. (2005) Reference values of oxidative stress parameters (MDA, SOD, CAT) in dogs and cats. Comparative Clinical Pathology. 13, (4 ), 190 – 194, 2005 .

  6. Gadjeva V, D. Kuchukova, R. Georgieva (2005). Influence of polychemotherapy on the antioxidant levels and lipid peroxidation in patients with lymphoproliferative diseases. Comparative Clinical Pathology 14, (1)13-18.

  7. Gadjeva V, D. Kuchukova, R. Georgieva. (2005). Vitamin combination Reduce Oxidative Stress and Improve Antioxidant Status in Patients with Iron Deficiency Anemia. Comparative Clinical Pathology 14, (1), 99-104.

  8. Koinarski V., Georgieva N., Gadjeva V., Petkov P. Antioxidant status of broiler chickens, infected with Eimeria acervulina (2005) Revue de Medecine Veterinaire, 156 (10), pp. 498-502. .(IF= 0,148)



2006

  1. Tanchev S and V. Gadjeva. (2006). Influence of antigen stimulation on the oxidative burst in inbred and outbreed rabbits. Revue de Medecine Veterinare . 157, 08-09, 1-5.(IF= 0,148)

  2. Georgieva NV, Koinarski V, Gadjeva V. Antioxidant status during the course of Eimeria tenella infection in broiler chickens. Veterinary Journal 172(3):488-92. 2006. (IF = 1, 25)


2007

  1. Gadjeva V, Tolekova A, Vasileva M. (2007). Effect of spin labeled 1-ethyl-1-nitrosourea on CCNU – induced oxidative injury. Die Pharmazie. 62(8):608-13 (IF = 0, 696)

  2. Zheleva А., Tolekova А., Zhelev M., Uzunova V., Platikanova M., Gadzheva V. Free radical reactions might contribute to severe alpha amanitin hepatotoxicity – a hypothesis, Medical Hypotheses, (2007), 69(2):361-7 (IF=0.920)

  3. Valcheva-Kuzmanova S., V. Gadjeva, D. Ivanova and A. Belcheva. Antioxidant activity of Aronia melanocarpa fruit juice in vitro Acta Alimentaria, Vol. 36 (4), pp. 425–428 (2007). (IF=0.274)

  4. Gerenova J. and Gadjeva V. (2007) Influence of methimazole treatment on parameters of oxidative stress in patients with Grave’s diseases. Comp Clin Pathol. 16, (4), 259-264

  5. Gerenova J., V. Gadjeva. Oxidative stress and antioxidant enzyme activities in patients with Hoshimoto’s thyroiditis. Comp Clin Pathol. 16, (4), 259-264, 2007


2008

  1. Bakalova R, Zhelev Z, Aoki I, Masamoto K, Mileva M, Obata T, Higuchi M, Gadjeva V, Kanno I. Multimodal silica-shelled quantum dots: direct intracellular delivery, photosensitization, toxic, and microcirculation effects. Bioconjug Chem. (2008), 19(6):1135 (IF=4,384)

  2. Gadjeva V, Dimov A, Georgieva N. Influence of therapy on the antioxidant status in patients with melanoma. J Clin Pharm Ther. (2008), 33(2): (IF=1,164)

  3. Bakalova R, Zhelev Z, Gadjeva V. Quantum dots versus organic fluorophores in fluorescent deep-tissue imaging - merits and demerits.Gen Physiol Biophys. 2008, 27(4):231-42. (IF=0,697)


2009

  1. Zhelev Z, Bakalova R, Aoki I, Matsumoto K, Gadjeva V, Anzai K, Kanno I. Nitroxyl radicals as low toxic spin-labels for non-invasive magnetic resonance imaging of blood-brain barrier permeability for conventional therapeutics. Chem Commun (Camb). 2009 7;(1):53-5. (IF=5,141)

  2. Zhelev Z, Bakalova R, Aoki I, Matsumoto K, Gadjeva V, Anzai K, Kanno I. Nitroxyl radicals for labeling of conventional therapeutics and noninvasive magnetic resonance imaging of their permeability for blood-brain barrier: relationship between structure, blood clearance, and MRI signal dynamic in the brain. Mol Pharm. 2009;6(2):504-12 (IF=4,612)

  3. Zhelev Z, Ken-Ichiro Matsumoto, Veselina Gadjeva, Rumiana Bakalova, Ichio Aoki, Antoaneta Zheleva and Kazunori Anzai. EPR signal reduction kinetic of several nitroxyl derivatives in blood in vitro and in vivo. Gen Physiol Biophys. 2009, 28(4):356-362. (IF=0,56)

2010

  1. Adhikari M, Arora R, Chawla R, Sharma J, Dhaker AS, Gupta D, Dubey N, Kumar R, Ivanov V, Gadjeva V, Gevrenova R, Sharma RK. Evaluation of silymarin as a promising radioprotector. Z Naturforsch C. 2010;65(5-6):337-46 (IF=0,720)

  2. Sudha Rana, Raman Chawla, Raj Kumar, Shefali Singh, Antoaneta Zheleva, Yanka Dimitrova, Veselina Gadjeva, Rajesh Arora, Sarwat Sultana, Rakesh Kumar Sharma. Electron Paramagnetic Resonance Spectroscopy in Radiation Research: Current Status and Perspectives. Journal of Pharmacy and Bioallied Sciences 2(2), 80-87, 2010. (IF 1.165)

  3. Kumar R, Bansal DD, Patel DD, Mishra S, Karamalakova Y, Zheleva A, Gadjeva V, Sharma RK. Antioxidative and radioprotective activities of semiquinone glucoside derivative (SQGD) isolated from Bacillus sp. INM-1. Mol Cell Biochem. 2010 Nov 30. (IF=1,896)

  4. Zhelev Z, Bakalova R, Aoki I, Gadjeva V, Kanno I. Imaging of cancer by redox-mediated mechanism: a radical diagnostic approach. Mol Biosyst. 2010 Dec 8;6(12):2386-8. (IF=4,015)

  5. Kumar R, Sharma RK, Bansal DD, Patel DD, Mishra S, Miteva L, Dobreva Z, Gadjeva V, Stanilova S. Induction of immunostimulatory cytokine genes expression in human PBMCs by a novel semiquinone glucoside derivative (SQGD) isolated from a Bacillus sp. INM-1. Cell Immunol. 2011;267(1):67-75. Epub 2010 Nov 19 (IF= 1,998).


2011

  1. Popov B, S. Georgieva, V. Gadjeva and V. Popov. Radioprotective, anticlastogenic and antioxidant effects of total extract of Haberlea Rhodopensis on rabibit blood samples exposed to gamma radiation in vitro. Revue de Medicine Veterinaire .2011, 162,1,34-39 (IF= 0,198).

  2. Rajesh Arora, AS Dhaker, J Sharma, M Adhikari, R Chawla, D Gupta, A. Zheleva, Y. Karamalakova, Raj Kumar, Raj K. Sharma, A Sharma, RK Sharma, Veselina Gadjeva. Radical Scavenging and Radiomodulatory Effects of Extracts of Psoralea corylifolia Linn. Evaluated by in vitro Assays and EPR Spectroscopy Z. Naturforschung 66c. 35-46 (2011). (IF=0,720)

  3. Kumar R, Sharma RK, Bansal DD, Patel DD, Mishra S, Miteva L, Dobreva Z, Gadjeva V, Stanilova S. Induction of immunostimulatory cytokine genes expression in human PBMCs by a novel semiquinone glucoside derivative (SQGD) isolated from a Bacillus sp. INM-1.

Cell Immunol. 2011;267(1):67-75. Epub 2010 Nov 19. (IF=2,575)

  1. Kumar R, Bansal DD, Patel DD, Mishra S, Karamalakova Y, Zheleva A, Gadjeva V, Sharma RK. Antioxidative and radioprotective activities of semiquinone glucoside derivative (SQGD) isolated from Bacillus sp. INM-1. Mol Cell Biochem. 2011 Mar;349(1-2):57-67. Epub 2010 Nov 30. (IF=2,168)

  2. Rajesh Arora, R Chawla, J Sharma, Anntoaneta Zheleva, Yanka Karamalakova, R Kumar, D Gupta, A Sharma, RK Sharma, V Gadjeva. Evaluation of Antioxidant and Radioprotective Properties of Rutin by In vitro/Ex vivo Studies and Electron Paramagnetic Resonance. European Journal of Agriculture (in press).


2012


  1. Zhelev Z, Gadjeva V, Aoki I, Bakalova R, Saga T. Cell-penetrating nitroxides as molecular sensors for imaging of cancer in vivo, based on tissue redox activity. Mol Biosyst. 2012 Aug 28;8(10):2733-40. (IF- 3.800)

  2. Manish Adhikari, Atlar Singh Dhaker, Jawahar Singh Adhikari, Veselin Ivanov, Vijay Singh, Raman Chawla, Raj Kumar, Rakesh Sharma, Yana Karamalakova, Veselina Gadjeva and Rajesh Arora. In vitro studies on radioprotective efficacy of silymarin against γ-irradiation. International Journal of Radiation Biology. 2012. doi/abs/10.3109/09553002.2013.741285. (IF- 2.275)

  3. Zhelev Z, Aoki I, Gadjeva V, Nikolova B, Bakalova R, Saga T. Tissue redox activity as a sensing platform for imaging of cancer based on nitroxide redox cycle. Eur J Cancer. 2012 Dec 19. doi:pii: S0959-8049(12)00860-X. 10.1016/j.ejca.2012.10.026. (IF 5.536)


2013

  1. Adhikari M, Dhaker AS, Adhikari JS, Ivanov V, Singh V, Chawla R, Kumar R, Sharma R, Karamalakova Y, Gadjeva V, Arora R. In vitro studies on radioprotective efficacy of silymarin against γ-irradiation. Int J Radiat Biol. 2013 Jan 10. [Epub ahead of print]

  2. Arora, R., Chawla, R., Sharma, J., Zheleva, A., Karamalakova, Y., Kumar, R., Gupta, D., Sharma, A., Sharma, R.K., Gadjeva, V. Antioxidant and radioprotective properties of rutin isolated from Nothapodytes Foetida (Wight) Sleumer established by in vitro/ex vivo studies and electron paramagnetic resonance. J.C.E.A.. (in press).

  3. Zheleva, A.M., Karamalakova, Y., Nikolova, G., Gadjeva, V. New possibilities for treatment of amatoxin intoxications: an EPR spectroscopy study on free radical formation caused by the mushroom toxin alpha amanitin. P.J.P.S. (in press) (IF=1.103)



I.2. Научни статии, публикувани в български ПЕРИОДИЧНИ ИЗДАНИЯ: (общ импакт фактор: 0. 24; индивидуален: 0.123)

1989

  1. Gadjeva V, Е. Raikova, Z. Raikov, Ts. Ivanova, M. Stefanova: Investigation of some physicochemical properties of new nitrosoureal derivatives-potential antitumour agents. Compt. Rend. Acad. Bulg. Sci. 42(7), 131-134, 1989. (IF= 0.08)

  2. Желева А., В. Гаджева, З. Райков, М. Иларионова, Д. Тодоров: Синтез и противотуморна активност на 1-(2-хлоретил)-1-нитрозо-3-(2-метил-1-пропанол-2-ил)-урея. Онкология 26(1), 29-32, 1989.

1991

  1. Гаджева В., М. Иларионова, З. Райков, Д. Тодоров: Биологична активност и токсичност на нови 1-алкил-1-нитрозо-3-циклохексилурейни аналози на CCNU. Онкология 28(3), 18-22, 1991.

1998

  1. Gadjeva V., R. Koldamova and J. Lazo: Construction of N- and C-terminal Deletion mutants of Human Bleomycin Hydrolase (hBH) and Determination of Oligomerization, Bleomycin Hydrolase and Cysteine Proteinase Activities of hBH and Deletion Mutants. Compt. Rend. Acad. Bulg. Sci. 52(11-12), 1999. (IF- 0.08)


1999

  1. Hristakieva, E., Gadjeva, V., Popova, S. Oxidative stress in psoriatic and vitiligo patients. Bulgarian Medicine, (7), 5-6: 45-47, 1999.

  2. Raikov, Z., Raikova, E., Zheleva, A., Gadzheva, V., Nitric oxide and nitroxyde in the mechanism of biological activity of the spin labeled compounds. Bulgarian Medicine, 3-4: 60-63, 1999.

2000

  1. Гаджева В., Т.Влайкова, С. Попова, Е. Христакиева, В. Иванова, П. Гойчева, Д. Христозов. Реактивни кислородни видове, антиоксидантни ензими и значението им за някои заболявания. Обзор I част. Българска медицина, (8), 5, 21-24, 2000.

  2. Христакиева E, В. Гаджева. Изследване фагоцитната функция на гранулоцити чрез супероксид анион продукцията в кръв от пациенти с псориазис и витилиго. Българска Медицина. 8(6), 2000.

  3. Иванова В, В. Гаджева, Т. Влайкова, С. Попова, И. Чакърски. Корелация между каталазна активност и липидно перокисление в кръв на пациенти с хематологични заболявания. Българска Медицина. 8(6), 2000.


2003

  1. Stanilova S., Z Karakolev, G. Dimov, Z. Dobreva, E. Slavov, V.  Gadjeva. Production of pro- and antiinflamatory cytokines, apoptosis and oxidative stress are essential for the outcome in severe sepsis. Trakia J Sciences. (1) 1, 42-48, 2003.

  2. Hristakieva E. and  V.  Gadjeva. Seasonal variations in the activity of antioxidant enzymes and lipis peroxidation in psoriatic and vitiligo patients. Trakia J Sciences. (1) 1, 27-31, 2003.

  3. Zheleva A, V. Gadjeva, M. Zhelev. Free radical formation might contribute to the severe amatoxin hepatotoxicity. Trakia Journal of Sciences, (1), 3, pp 42-45 , 2003.


2004

  1. Georgieva N., Gadjeva, V., Tolekova A. New isonicotinoylhydrazones with SSA protect against oxidative-hepatic injury of isoniazid. Trakia J Sciences. (2), 1, 37-43, 2004.

  2. Georgieva N, V. Gadjeva, D. Dimitrova. Study on the influence of Isoniazid alone or combined with newsynthetized isoniazid structural analogues upon catalase activity. Bulgarian J Veterinary Medicine, 7(1), 9-16, 2004.

  3. Геренова Ж., Гаджева В., Попова С., Боева С., Пенкова Д. (2004). Антиоксидантен статус при пациенти с хипотиреоидизъм. Ендокринология, IX (4), 195-201.

  4. Zheleva A., V. Gadjeva, S. Popova. Antioxidant properties of amanita phaloides mushroom toxins. Trakia J Sciences 2(3), 28-30, 2004


2005

  1. Gadjeva V., D. Kuchukova, E. Aladjov, R. Georgieva, (2005). Correlation between plasma malondialdehyde and ceruloplasmin activity in patients with malignant hematological diseases. Trakia J Sciences, 3(2) 29-34.

  2. Gerenova J. and Gadjeva V. (2005). Changes in parameters of oxidative stress in patients with Graves’diseases. Trakia J Sciences,3(4), 32-36.

  3. Dobreva Z., Gadjeva V, Stanilova S. (2005). Comparative study of the effect of spin-labelled 1-ethyl-1-nitrosourea and CCNU on the specific antibody production. Trakia J Sciences,3(3), 20-26.

  4. Гаджева В., Попов Б, Димов А. (2005). Влияние на химиотерапия с Дакарбазин върху подбрани параметри на оксидативния стрес при пациенти с меланом. Trakia J Sciences,3(Suppl. 1), 79-83.

  5. Георгиева, Н., Д. Кючукова, В. Гаджева, (2005). INH и екологичното оксидативно равновесие в кръв на плъхове. Trakia J Sciences, 3 (1), 21-23.

  6. Georgieva, N., V. Gadjeva, V. Koinarski, M. Gabrashanska, M. Galvez M, (2005). Influence of newly synthesized glycin-zinc salt upon some parameters of oxidative stress in Eimeria acervulina infected broiler - chickens. Ecology and Future, IV (4), 34 – 39.


2006

  1. Gadjeva V., (2006). Role of ROS in the modulation of angiogenesis, Antiangiogenic action of antioxidants.Mini Review. Compt. Rend. Acad. Bulg. Sci. 59(4), 443-453. (IF= 0.08)

  2. Goycheva P., Gadjeva V., Popov B. (2006). Oxidative stress and its complications in diabetes mellitus. Trakia J Sciences,4(1), 1-8.

  3. Popov B., V. Gadjeva, P. Valkanov, A. Tolekova, V. Uzunova. Superoxide dismutase and catalase activities in gliomas. Buldarian medicine, 13 (1), 14-17, 2006.


2007

  1. Gojcheva P., B. Popov, V.Gadjeva. (2007). Interdependence between quantity of malondialdehyde, changes in the activity of superoxide dismutase and catalase and the development of microvascular complications in type 2 diabetes. Folia medica XLIX (1).

  2. Толекова А., Г. Илиева, Б. Попов, С. Попова, В. Гаджева и Т. Мирчева. Влияние на терапията с рекомбинантен еритрипоетин върху оксидативния стрес при пациенти с хронична бъбречна недостатъчност. Медицински преглед, 43,(4), 55-59, 2007.

  3. Гойчева П., Б. Попов, В. Гаджева и С. Попова. Липидна пероксидация при захарен диабет. Медицински преглед, 43, (3), 69-74, 2007

  4. Анталавичева М., П. Гойчева, А. Толекова, Б. Попов, С. Попова, В. Гаджева. Анализ на плазмената концентрация на Малондиалдехид при пациенти с и без диабетна нефропатия като проява на оксидативен стрес. Trakia J Sciences, vol 5, suppl.1, pp79-82, 2007.

  5. Tsoneva M., A. Tolekova , V. Gadjeva. Influence of vitamin E on oxidative stress parameters in liver homogenates of mice treated with Cychlomin. Trakia J. Sciences 2007, 5(1), suppl 1, 21-25.


2008

  1. Ganeva MG, Getova DP, Gadjeva VG. Adverse drug reactions and reactive oxygen species. Folia Med (Plovdiv). 2008;50(1):5-11.

  2. Попов Б., В. Гаджева, П. Вълканов, А. Толекова и С. Попова. Липидно перокисление и активност на супероксид дисмутаза и каталаза в астроцитоми. Медицински преглед 44, (2), 2008.

  3. Goycheva P., Tolekova A., Popov B., Popova S., Gadzheva V., Koycheva R., and Sapundzhiev D. Analysis of activity of superoxide dismutase and catalase and plasma malondialdehyde concentration in patients with insulin-dependent diabetes mellitus, undergoing haemodialysis with polysulfone and cellulose diacetate membranes. Медицински преглед. 2008, 44(2), 44-49.

  4. Tsoneva M., P. Gaicheva, A. Tolekova, V. Gadjeva. Influence of spin-labeled antioxidants on oxidative toxicity of cytostatic therapy and ionizing radiation. Trakia J. Sciences, 2008, 6(1), suppl.1, 32-36.

  5. Гойчева П., А. Толекова, Б. Попов, С. Попова, В. Гаджева, П. Койчева, Д. Сапунджиев. Анализ на активностите на супероксиддисмутаза и каталаза и на плазмената концентрация на малондиалдехид при пациенти с и без диабетна нефропатия. Trakia J Sciences, 2008, 6(2), Suppl. 2, 188-192.


2010

  1. Zh. Zhelev, R. Bakalova, S. Shibata, V. Gadjeva, L. Spasov, I. Aoki MAGNETIC RESONANCE IMAGING OF BRAIN NEUROBLASTOMA BASED ON
    NITROXIDE REDOX CYCLE. Trakia Journal of Sciences. Volume 8, 2010, Supplement 2,

  2. Galina Nikolova, Yanka Karamalakova, Tsvetelin Georgiev, Petya Hadzhibozheva, Anna Tolekova, Veselina Gadjeva, Antoaneta Zheleva. Severe mushroom toxin alpha amanitin causes generation of lipid radicals in liver tissues of mice –a comperative study by two different instrumental methods. Trakia Journal of Sciences. 2010, , v 8 suppl.2, 149-154

  3. Yanka Karamalakova, Galina Nikolova, Iliana Ionkova, Tsvetelin Georgiev, Petya Hadzhibozheva, Anna Tolekova, Veselina Gadjeva, Rajesh Arora, Rakesh K. Sharma, Antoaneta Zheleva. Comparative EPR in vitro and ex vivo spectroscopy study of the levels of lipid peroxidation processes in livers and kidneys of mice after treatment by naturally isolated antioxidants. Trakia Journal of Sciences. 2010, v 8 suppl.2, 137-143.

  4. Yanka Karamalakova, Galina Nikolova , Tsvetelin Georgiev, Petya Hadzhibozheva, Anna Tolekova, Veselina Gadjeva , Antoaneta Zheleva. Generation of lipid radicals in mice liver and kidney tissues after treatment by spin labelled nitrosoureas – an ex vivo epr spectroscopy study. Trakia Journal of Sciences. 2010, v 8 suppl.2, 144-148.

  5. Nikolova, G., Karamalakova,Y., Georgiev, Ts.,  Hadzhibozheva, P., Tolekova, A., Gadjeva, V., Zheleva, A. Severe mushroom toxin alpha amanitin causes generation of lipid radicals in liver tissues of mice – a comperative study by two different instrumental methods. Trakia J. Sci., vol. 8 suppl. 2, 149-154, 2010.


2011

  1. B. Popov, Sv. Georgieva, V. Gadjeva. MODULATORY EFFECTS OF TOTAL EXTRACT OF HABERLEA RHODOPENSIS AGAINST THE CYCLOPHOSPHAMIDE INDUCED GENOTOXICITY IN RABBIT LYMPHOCYTES IN VIVO. Trakia Journal of Sciences. 2010, v 9 (l), 51-57.

  2. Yanka Karamalakova, Krishna Chuttani, Antoaneta Zheleva, Anil K. Mishra, Vesselina Gadjeva. ROS production, Radiolabelling, biodistribution and gamma scintigraphy in healthy and tumor bearing mice after single treatment by two different 2-chloroethylnitrosoureas. X International Congress of Medical Sciences, Sofia, Bulgaria 13-16 May, 2010. Tribuna Medica Supplement to issue 1/2011, Volume LXII

  3. AS Dhaker, Y Karamalakova, R Kumar, RK Sharma, S Sultana, A Zheleva, V Gadjeva, Rajesh Arora. EPR Spectroscopic Correlation of Antimicrobial, and Radiomodulatory Properties of Psoralea corylifolia Linn. X International Congress of Medical Sciences, Sofia, Bulgaria 13-16 May, 2010. Tribuna Medica Supplement to issue 1/2011, Volume LXII

  4. Zheleva, A., Karamalakova, Y., Nikolova, G., Kumar, R., Sharma, R., and Gadjeva, V. A new antioxidant with natural origin characterized by Electron Paramagnetic Resonance spectroscopy methods. BIOTECHNOL BIOTEC EQ DOI: 10.5504/50YRTIMB.2011.0027, (IF=0.760).

  5. Karamalakova, Y., Sharma, J., Sharma, R.K., Gadjeva, V., Kumar, R., and Zheleva, A. Comparative investigation on radical scavenging activity and protective properties of natural isolated and synthetic antioxidants. BIOTECHNOL BIOTEC EQ, DOI: 10.5504/50YRTIMB.2011.0032, (IF=0.760).

  6. Georgieva, E., Karamalakova, Y., Nikolova, G., Grigorov, B., Pavlov, D., Gadjeva, V., Zheleva, A. Radical scavenging capacity of seeds and leaves ethanol extracts of Cynara Scolymus L. – a comparative study. BIOTECHNOL BIOTEC EQ, DOI: 10.5504/50YRTIMB.2011.0028, (IF=0.760).


2012


  1. Karamalakova, Y., Nikolova, G., Stanev, S., Arora , R., Gadjeva, V. and Zheleva, A. Investigation of antioxidant property and protective effect of Lavandulla Angustifolia Mill after radiation. Biothechnology& Biothechnological Equipment (IF=0.706)

  2. Nikolova, G., Karamalakova, Y., Georgiev, T., Hadzhibozheva, P., Gadjeva, V., Tolekova, A., and Zheleva, A. Ex vivo EPR evaluation of oxidative stress biomarkers in diabetes induced wister rats. Trakia J. Sci., vol. 10 suppl.1, 52-57, 2012.

  3. Sharma, J.,Chawla, R., Karamalakova, Y., Kumar, R., Sharma, R. K., Zheleva, A., Gadjeva, V., and Arora, R. Investigation of the modulatory role of Bacopa Monnierri (L.) pennel extracts against radiation-induced oxidative stress and antioxidant status in vitro. Trakia J. Sci., vol. 10 suppl.1, 1-7, 2012.

  4. Adhikari, M., Karamalakova, Y., Ivanov, V., Gadjeva, V., Kumar, R., Sharma, R. K., Zheleva, A., and Arora, R. A comparative evaluation of an antioxidant of natural origin derived from Silybum marianum characterized by in vitro assays and electron paramagnetic resonance spectroscopy. Trakia J. Sci., vol. 10 suppl.1, 17-24, 2012.

  5. Karamalakova, Y., Chuttani, K., Gadjeva, V., Zheleva, A., and Mishra, A.K. Radiostability and biological evaluation of new class nitroxyl-labelled agents as radiotracers. Trakia J. Sci., vol. 10 suppl.1, 73-78, 2012.

  6. Nikolova, G., Mancheva, V., Karamalakova, Y., Grigorov, B., Manchev, I., Zheleva, A., Gadjeva, V. Effect of Madopar therapy on two oxidative stress boimarkers in patients with Parkinson Disease - a comparative study. Trakia J. Sci., vol. 10 suppl.1, 46-51, 2012.

  7. Sharma, J.,Chawla, R., Karamalakova, Y., Kumar, R., Sharma, R. K., Zheleva, A., Gadjeva, V., and Arora, R. Modulation of radiation-mediated damage by Cuscuta Relexa Linn. Trakia J. Sci., vol. 10 suppl.1, 58-64, 2012.

  8. Karamalakova, Y., Kumar, R., Gadjeva, V.,Tripathi, R., Sharma, R. K., Zheleva, A. EPR investigations on scavenging capacity and antioxidant activity of IBG-20 a fraction isolated from Bacillus sp. INM-1. Trakia J. Sci., vol. 10 suppl.1, 34-39, 2012.

  9. Yanka Karamalakova, Ekaterina Georgieva, Rajesh Arora, Rakesh Sharma, Galina Nikolova, Veselina Gadjeva, Antoaneta Zheleva. Investigation on the oxidative stress biomarkers and organ biodistribution of Psoralea corylifolla Linn. J. BioSci. Biotech. SE/ONLINE: 67-71, 2012.

2013

  1. Karamalakova, Y., J. Sharma, J., Nikolova, G., Stanev, S., Arora , R. , Gadjeva, V., and Zheleva, A. Studies on antioxidant properties before and after UV- and γ-radiation of Bulgarian lavender essential oil isolated from Lavandula Angostifolia Mill. BIOTECHNOL BIOTEC EQ, (in prees.) (IF=0.760).



I.3. Научни ДОКЛАДИ, публикувани в ПЪЛЕН ТЕКСТ В СБОРНИЦИ ОТ НАУЧНИ ФОРУМИ:

1987

  1. Гаджева В. Тирозинсъдържаща нитрозоурея. II Обединена Научна сесия пет години ВМИ Стара Загора, 2-3 октомври, 1987. Доклад депозиран в ЦНТБ под No НД 2851/88/

1992

  1. Gadzheva V., E. Raikova: Physico-chemical properties of de novo synthesized spin-labeled and non-labeled nitrosoureas. Annuaire de L’Institut superieur de Medicine de Stara Zagora, 3, 53-58, 1992

1993

  1. Gadzheva V., K. Ichimory, H. Nakazawa: Superoxide Scavenging Activity of Spin-labeled Anticarcinogen with Nitrosourea or Triazene Moiety. International Association on Electron Paramagnetic Resonance Spectroscopy, Annual Proceedings (Scientific papers), pp.69-72, 1993, Kyoto, Japan

1996

  1. Колдамова Р., И. Лефтеров и В. Гаджева: Определяне на хромозомни аберации след третиране на човешки лимфоцити in vitro c Bleomycin и три хлоретилнитрозоуреи.. Annual of the Higher Medical Institute of Stara Zagora. 6(6), 13-14, 1996

  2. Желева А., В. Гаджева, З. Райков: Образуване на свободни радикали от противотуморния препарат CCNU след УВ облъчване в полярна и неполярна среда. Annual Proceedings (Scientific papers), International Medical Association Bulgaria. 2(2), 1996

1997

  1. Vlaykova T., V. Gadzheva, P. Kraznik, Z. Raikov: The radiation chemistry and radiation biology investigations on some NU derivatives. Eight National Conference”Modern tendencies in the development of fundamental and applied sciences”, 5-6 June, 1997, Stara Zagora

1998

  1. Gadjeva V., A. Zheleva and K. Yankov: Comparative Analyze of the Dynamic Characteristics of the Process of Enzyme Oxidation of DL-DOPA to DOPA-chrome by Tyrosinase, Modulated by Spin-labeled Triazenes. Eight National Conference”Modern tendencies in the development of fundamental and applied sciences”, 4-5 June, 1998, Stara Zagora

  2. Vlaykova T., K. Yankov and V. Gadjeva: Changes in the Characteristics of DOPA-Oxidase Process, Catalyzed by Mushroom Tyrosinase, in the Presence of Triazene Derivatives. Eight National Conference”Modern tendencies in the development of fundamental and applied sciences”, 4-5 June, 1998, Stara Zagora.

  3. Gadjeva V. and R. Koldamova: Investigation the Significance of N- and C-terminus in Oligomerization of Human Bleomycin Hydrolase (hBH) by Gel filtration. Eight National Conference”Modern tendencies in the development of fundamental and applied sciences”, 4-5 June, 1998, Stara Zagora

  4. Gadjeva V. and R. Koldamova: Construction of N- and C-terminal Deletion Mutants of Human Bleomycin Hydrolase (hBH) and determination of Bleomycin Hydrolase and Cysteine Proteinase Activities of hBH and Deletion Mutants. Eight National Conference”Modern tendencies in the development of fundamental and applied sciences”, 4-5 June, 1998, Stara Zagora.


1999

  1. Lazarova G, V. Gadjeva. Effect of antioxidants on the cell growth of E. Coli treated with antitumor drug CCNU. Current trends in the development of fundamental and applied sciences, 2(1),54-60, 1999.

  2. Gadjeva V, G. Lazarova, A. Zheleva. Newly synthesized spin-labeled nitrosoureas and triazenes-nontoxic for E-coli bacteria cells. Current trends in the development of fundamental and applied sciences, 2(1),60-67, 1999.


2001

  1. Kuchukova D, V.Gadjeva, T. Vlaykova, V. Ivanova, R. Georgieva, Influence of chemotherapy on the antioxidant status in patients with various hematological diseases, Annual Proceedings IMAB vol 7(1), 111-113, 2001.


2002

  1. Kutchukova D, V. Gadjeva and R. Georgieva. Influence of schemes of chemotherapy on free radical damage of patients with malignant hematological diseases. Scientific conference with international partipations. Union of scientists. 6-7 June , Human medicine, vol.3,172-175, 2002.

  2. Gadjeva Veselina. Oxidative stress and human diseases. Scientific conference with an international partipations. Union of scientists. 6-7 June, Human medicine, vol.3,139-142, 2002.

  3. Гаджева В, Д. Кючукова, В. Иванова. Изследване фагоцитната функция на гранулоцити чрез продукцията на супеоксиден анион при пациенти със злокачествени хематологични заболявания. Юбилейна научна конференция, Медицински факултет. 18-20 okтомври, Том 2, 2-7, 2002.

  4. Тодорова И, Г. Симеонова, Д. Кючукова, Д. Динев, В. Гаджева. Изследване показателите на оксидативния стрес в кръв на домашни любимци-кучета и котки. Юбилейна научна конференция, Медицински факултет. 18-20 okтомври , Том 2, 55-60, 2002.

  5. Христакиева Е, В. Гаджева. Оксидативен стрес при някои дерматологични заболявания. Сборник от Юбилейна Научна конференция с международно участие; 18-20 okтомври, 2002; том 2 Клинична медицина, Стара Загора,172-176

  6. Георгиева, Н., В. Гаджева, Д. Димитрова. Изследване възможностите за намаляване хепатотоксичността на изониазида чрез комбинации с изоникотиноилхидразони с антиоксидантна активност. Юбилейна научна конференция с международно участие, МФ, Тр.У., 18-20 октомври, Стара Загора, 1, 70-74, 2002.


2003

  1. Христакиева Е, В. Гаджева. Корелация между показателите на оксидативния стрес и активността на заболяването при пациенти с псориазис. Научна конференция с международно участие 5-6 юни 2003 Стара Загора, том ІІІ Издателство “Съюз на учените-Стара Загора”; 40-44.

  2. Георгиева Н, В. Гаджева, А. Толекова. Ефект на изониазид и изоникотиноилхидразони върху активността на антиоксидантния ензим супероксид дисмутаза. Научна конференция с международно участие, 5-6 юни, Съюз на учените, Стара Загора, Том 3, Хуманна Медицина, 157-161, 2003.


2005

  1. Узунова В., А. Толекова, Г. Илиева, В. Гаджева., Б. Попов, Т. Мирчева, Д. Сапунджиев, И. Чакърски. Оксидативен стрес и терапия с еритропоетин mри хронична бъбречна недостатъчност. Научна конференция с международно участие “Стара Загора 2005” , (Сборник с доклади), т.4, 385-391, 2005.


2006

  1. Чекъров А., С. Папачева, А. Толекова, Г. Илиева, В. Гаджева, Б. Попов, Т. Мирчева, И. Чакърски. Влияние на лечението с еритропоетин върху оксидативния стрес при болни с хронична бъбречна недостатъчност. Международна научна конференция “Науката в условията на глобализацията през ХХІ век” Стара Загора, (Сборник с доклади), т.4, 164-168, 2006.



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