Литература: Al-Khadra A, Nikolski V, Efimov ir

К О Н С П Е К Т

1. 
   Електропорация (електропермеабилизация). Кратко описание на феномена.
   
2. 
   Електрохимиотерапия. Пренасяне на цитотоксични лекарства и генен материал през мембраната на клетката.Обратима и необратима електропорация.
   
3. 
   Трансмембранно напрежение, индуцирано в изолирана клетка чрез генериране на електрично поле. Формула на Schwan. Модели отчитащи проводимостта на мембраната, цитоплазмата и външната среда. Ограничения при аналитичното описание на електричното поле за сфероидалната форма на клетката.
   
4. 
   Електропорация в клетъчна суспенсия и тъкани.
   
5. 
   Техники за индуциране на електрично поле в клетката. Генериране на електрични импулси.
   
6. 
   Влияние на параметрите на електричните импулси върху степента на електропермеабилизация.
   
7. 
   Оптимизация на параметрите на електричните импулси.
   
8. 
   Ефекти от генериране на нисковолтово високочестотно поле.
   
9. 
   Риск от фибрилация.
   
10. 
    Електроди.
    
11. 
    Генератори на високоволтови импулси.
    

1. 
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2. 
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3. 
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4. 
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5. 
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6. 
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7. 
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8. 
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9. 
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10. 
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11. 
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12. 
    Mali B, Jarm T, Corovic S, Snezna M, Paulin-Kosir, Cemazar M, Sersa G, Miclavcic D (2008): ‘The effect of electroporation pulses on functioning of the heart’, Med Biol Eng Comput, 46, 745-757.
    
13. 
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14. 
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15. 
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16. 
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17. 
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18. 
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19. 
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20. 
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21. 
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22. 
    Seok Chan Kim (2008): ‘Electroporation by strong interval defibrillation shock in intact structurally normal and chronically infracted rabbit hearts’, MSc degree, Case Western Reserve University, pages 49.
    

pdf.cgi/Kim%20Seok%20Chan.pdf?acc_num=case1196122659

23. 
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24. 
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25. 
    Yu Zhou, Fang Fang, Jianjun Chen, Huadong Wang, Haiyan Chang, Zhongdong Yang, Ze Chen (2008): ‘Electroporation at Low Voltages Enables DNA Vaccine to Provide Protection against a Lethal H5N1 Avian Influenza Virus Challenge in Mice’, Intervirology, 51, 241-246, doi: 10.1159/000156483.