Невролептици Производни на фенотиазина



Дата15.03.2017
Размер17.06 Kb.
Невролептици


  1. Производни на фенотиазина* :

    • Chlorpromazine*

2-chloro-10-(3-dimethylaminopropyl) phenothiazine




  • Levomepromazine


2-methoxy-10-(2-methyl-3-dimethyl aminopropyl)phenothiazine



  • P
    rochlorperazine

3-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine



  • T
    rifluoperazine

2-trifluoromethyl-10-[3`-(1-methyl-4-piperazinyl)propyl]phenothiazine


  • T
    hioproperazine (Majeptil)

3-dimethylsulfamoyl-10-[3-(4-methylpiperazino)propyl]phenothiazine


  • F
    luphenazine

2-(trifluoromethyl)-10-[3-[1-(β-hydroxyethyl)-4-piperazinyl]propyl]phenothiazine



  • Thioridazine

2-methylmercapto-10-[2-( N-methyl-

2-piperidyl)ethyl]phenothiazine


  • P
    ericiazine (Neuleptil)

2-cyano-10-[3-(4-hydroxypiperidino)propyl]phenothiazine


  1. Производни на тиоксантена :

  • Chlorprothixene

α-2-chloro-10-

(3-dimethylaminopropylidene) thioxanthene



  • F
    lupentixol (FLUANXOL®)

2-trifluoromethyl-9-[3-[4-(β-hydroxyethyl)-1-piperazinyl]propylidene]thioxanthene


  • Clopenthixol (Clopixol)

2-chloro-9-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propylidene]thioxanthene



  1. Бутирофенони :

  • H
    aloperidol

4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone



  • D
    roperidol

1-[1-[4-(4-Fluorophenyl)-4-oxobutyl]-1,2,3,6-tetrahydro-4-pyridinyl]-1,3-dihydro-

2H-benzimidazol-2-one




  1. Дифенилбутилпиперидини :

  • P
    imozide (Orap)

1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-

2-one


  • F
    luspirilene (Imap)

8-[4,4-Bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one




  • P
    enfluridol (Semap®)

1-[4,4-Bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-

4-piperidinol




  1. С друг строеж :

  • Clozapine (Leponex®)


8-Chloro-11-(4-methyl-1-piperazinyl)-

5H-dibenzo[b,e][1,4]diazepine



  • Loxapine (Cloxazepin)

2-Chloro-11-(4-methyl-1-piperazinyl) dibenz[b,f][1,4]oxazepine





  • R
    isperidone

3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-

2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one







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