Advanced ovarian cancer as a risks of primary multiple malignant tumors after the treatment of extra genital cancer
QUALITY OF LIFE AND DISTRESS IN WOMEN WITH GYNECOLOGIC CANCER
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QUALITY OF LIFE AND DISTRESS IN WOMEN WITH GYNECOLOGIC CANCER.G. CHAKALOVA (1), B.CHAKALOV (2)Int. J. Gynecol. Cancer, vol. 20, Suppl 2, October 2010, р. 803. National Oncologic Hospital, Clinic of gynecological Oncology, Sofia, Bulgaria (1) Medical Center Gineka, Sofia, Bulgaria (2) SUMMARY Purpose: This study investigates the changes in the quality of life (QOL) and the NCCN Distress Thermometer (DT) was administered to 103 women undergoing operation, radiation therapy or chemotherapy for gynecologic cancer over a one-year period. Method: All women who were undergoing their first treatment at the National Oncologic Hospital, Clinic of Gynecological Oncology, Sofia, Bulgaria. for either primary disease were asked to complete the assessment prior to that first treatment. Three, six, nine and twelve months after initial treatment the patients were asked to complete the same assessment. The patients were examined on three occasions using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-core30 (EORTC QLQ-C30).This report describes and the frequency and character of psychological distress in this population and examines the effect of disease, treatment, and demographic variables on levels of distress.The DT is a self-administered scale for patients to rate their level of distress from 0 to 10, where 0 represents no distress and 10 represents extreme distress. Further, patients are asked to choose from among 34 items that constitute sources of distress within the last week. Results: Although the global QOL and physical function decreased before discharge, the emotional function was lowest before surgery. Over half (57%) of women reported a score of 4 or greater on the DT and were then assessed by the oncology psychologist. Women who were younger than age 60 and single were more likely to be distressed. There were no associations between the type of cancer, stage of cancer, method of the treatment. Conclusions: A significant percentage (57%) of these women experienced distress at levels that indicate further evaluation is indicated. This study suggests that early screening and evaluation are essential in this group of cancer patients. Chakalova, G., Stage I adenocarcinoma versus stage I squamous cell carcinoma of the cervix. A long time follow up study. ResearchGate, 2013. https://www.researchgate.net/publication/233979622_STAGE_I_ADENOCARCINOMA_VERSUS_STAGE_I_SQUAMOUS_CEEL_CARCINOMA_OF_THE_CERVIX._A_LONG_TIME_FOLLOW_UP_STUDY?ev=prf_pub ABSTRACT From 1970 to 1991, 1416 patients with cervical cancer were treated and follow up to December 2002. Squamous cell carcinoma were in 1262 cases (89,1%) and adenocarcinoma were in 154 cases (10,9%). Stage I squamous cell cancer were 594 patients (47,5%), and Stage I adenocarcinoma were 72 patients (43,4%). Mean age 52,5 years in the adenocarcinoma group and 50,9 years in the squamous group were detected. We found an increase in adenocarcinoma group from 5,3% to 8,9%. The treatment were: Wertheim operation in 51 cases, Wertheim and radiation therapy in 249 cases, radiation therapy, Wertheim and postoperative radiation in 208 cases, brachitherapy and external radiation in 158 cases. Ten year therapeutic results were:569 patients are alive, and 97 patients are dead. In cases of squamous cell differentiation 85,9% are alive, and in cases of adeno-carcinoma 81,9 % are alive. In group with Wertheim operation and postoperative external radiation 92,4 % of the cases with squamous cell cancer and 89,5 % of the cases with adenocarcinoma are alive. The group with preoperative external radiation, Wertheim operation and postoperative external radiation 78,7 % of the cases with squamous cell and 72 % of the cases with adenocarcinoma are alive. In group treated by intracavitary brachitherapy and external radiation 80,8 % of the cases with squamous cell carcinoma and 71,4 % of the cases with adenocarcinoma are alive. There was no signi-ficant difference in survival treated surgically, and with operation and postoperative radiotherapy. In contrast, the difference in survival in squamous cell and adenocarcinoma high risk group with preoperative STAGE DETERMINATION OF THE SECOND TUMOR IN CASES OF PRIMARY MULTIPLE GYNECOLOGICAL CANCER G. CHAKALOVA Gynecological Clinic, National Oncologic Hospital, Sofia ABSTRACT Background: The aim of the study was to estimate the stage determination of the second tumor in cases of gynecological cancer. Materials and methods: Primary multiple malignant tumor in 1869 cases of gynecological cancer as a first tumor in Bulgaria during the period 1993-2010 according data from Bulgarian National Cancer Registry were analyzed. Results: The most frequent second tumor was: cancer of the breast (511 cases), colon-rectum (289 cases), lung (98 cases), bladder (79 cases) and stomach (51 cases). The second tumor was in more advanced stage than the first tumor. The second tumor was in: stage I- 25,6%, stage II- 20,9%, stage III-15,6%, stage IV-13,1%, and unknown stage in 24,9% cases. Cervical cancer in 453 cases, endometrial cancer in 919 cases and ovary cancer in 422 cases were found. When the first tumor is cervical cancer, the second one was found in stage I in 27,4%, and the rest stages were 18,5%, 13,5%, 15,7% and 24,9% respectively. When the first tumor is endometrial cancer, the second one was found in stage I in 26,4%, and the rest stages were 22,1%, 16,4%, 11,5% and 23,5% respectively. When the first tumor is ovary cancer, the second one was found in stage I in 22,5%, and the rest stages were 19,7%, 16,4%, 13,5% and 28,0% respectively. Conclusion: Our results indicated late diagnosis of the second tumor with worst prognosis after the treatment the gynecological cancer. We recommend target search of a second tumor at follow-up period of the patients with gynecological cancer. Каталог: assets -> files -> Nauka-SDO Nauka-SDO -> Конкурс за заемане на академична длъжност „Професор по научната специалност Nauka-SDO -> На избрани нерецензирани научни трудове Nauka-SDO -> Списък публикации Nauka-SDO -> Специализирана болница за активно лечение по онкология-еад Nauka-SDO -> Рецензия от проф. Д-р н. Гаврилова дм Изтегляне 1.05 Mb. Сподели с приятели:
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