S. P. Wasser1 Медицински гъби като източник на анти-туморни и имунно-модулиращи полизахариди

Gutiérrez A, Prieto A, Martínez AT (1996) Structural characterization of extracellular polysaccharides produced by fungi from the genus Pleurotus. Carbohydr Res 281:143–154

Hamuro J, Chihara G (1985) Lentinan, a T-cell oriented immunopotentiator: its experimental and clinical applications and possible mechanism of immune modulation. In: Fenichel RL, Chirigos MA (eds) Immunomodulation agents and their mechanisms. Dekker, New York, pp 409–436

Han SB, Lee CW, Jeon YJ, Hong ND, Yoo ID, Yag KH, Kim HM (1999) The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis. Immunopharmacol 41:157–164

Hara C, Kumazawa Y, Inagaki K, Kaneko M, Kiho T, Ukai S (1991) Mitogenic and colony stimulating factor-inducing activities of polysaccharide fractions from the fruit bodies of Dictyophora indusiata Fisch. Chem Pharm Bull (Tokyo) 39:1615–1616

Hawksworth DL (1993) The tropical fungal biota: census, pertinence, prophylaxis, and prognosis. In: Isaac S, Frankland JC, Watling R, Whalley AJS (eds) Aspects of tropical mycology. Cambridge University Press, Cambridge, UK, pp 265–293

Hawksworth DL (2001) Mushrooms: the extent of the unexplored potential. Int J Med Mushrooms 3:333–340

Hikichi M, Hiroe E, Okubo S (1999) Protein polysaccharide 0041. European Patent 0939082, 9 January 1999

Hirata A, Itoh W, Tabata K, Kojima T, Itoyama S, Sugawara I (1994) Anticoagulant activity of sulfated schizophyllan. Biosci Biotechnol Biochem 58:406–407

Hiroshi S, Takeda M (1993) Diverse biological activity of PSK (Krestin), a protein-bound polysaccharide from Coriolus versi­color (Fr.) Quél. In: Chang ST, Buswell JA, Chiu SW (eds) Mushroom biology and mushroom products. The Chinese University Press, Hong Kong, pp 237–245

Hobbs C (1995) Medicinal mushrooms: an exploration of tradition, healing and culture. Botanica Press, Santa Cruz, Calif.

Hobbs C (2000) Medicinal value of Lentinus edodes (Berk.) Sing. (Agaricomycetideae). A literature review. Int J Med Mushrooms 2:287–302

Ikekawa T (1995) Enokitake, Flammulina velutipes-host-mediated antitumor polysaccharides. Food Rev Int 11:202–206

Ikekawa T (2001) Beneficial effects of edible and medicinal mushrooms in health care. Int J Med Mushrooms 3:291–298

Ikekawa T, Uehara N, Maeda Y, Nakanishi M, Fukuoka F (1969) Antitumor activity of aqueous extracts of edible mushrooms. Cancer Res 29:734–735

Ikekawa T, Ikeda Y, Yoshioka Y, Nakanishi K, Yokoyama E, Yamazaki E (1982) Antitumor polysaccharides of Flammulina velutipes 2. The structure of EA-3 and further purification of EA-5. J Pharmacobiol Dyn 5:576–581

Ikekawa T, Saitoh H, Feng W, Zhang H, Li L, Matsuzawa T (1992) Antitumor activity of extracts and polysaccharides. Chem Pharm Bull (Tokyo) 40:1954–1957

Ishiyama D, Kawagishi H, Furukawa S, Mori Y, Kojima F, Okamoto K, Sakamoto H (1996) Eudesmane derivative and neurocyte factor-producing inducer containing the same as active ingredient. Japanese Patent 8073395, 19 March 1996

Ito H, Sugiura M, Miyazaki T (1976) Antitumor polysaccharide fraction from the culture filtrate of Fomes fomentarius. Chem Pharm Bull (Tokyo) 24:2575

Ito H, Shimura K, Itoh H, Kawade M (1997) Antitumor effects of a new polysaccharide-protein complex (ATOM) prepared from Agaricus blazei (Iwade strain 101) “Himematsutake” and its mechanisms in tumor-bearing mice. Anticancer Res 17:277–

Itoh H, Ito H, Amano H, Noda H (1994) Inhibitory action of a (1→6)-beta-D-glucan-protein complex (FIII-2-b) isolated from Agaricus blazei Murrill (“Himematsutake”) on Meth A fibrosarcoma-bearing mice and its antitumor mechanism. Jpn J Pharmacol 66:265–271

Itoh W, Sugawara I, Kimura S, Tabata K, Hirata A, Kojima T, Mori S, Shimada K (1990) Immunopharmacological study of sulfated schizophyllan (SPG) I: Its action as a mitogen and anti-HIV agent. Int J Immunopharmacol 12:225–234

Jong SC, Birmingham JM (1990) The medicinal value of the mushroom Grifola. World J Microbiol Biotechnol 6:101– 127

Kanayma H, Togami M, Adachi N, Fukai Y, Okumoto T (1986) Studies on the antitumor active polysaccharides from the mycelia of Poria cocos: III. Antitumor activity against mouse tumors. Yakugaku Zasshi 106:307–312

Karácsonyi ˇPleurotus S, Kuniak L (1994) Polysaccharides of ostreatus: isolation and structure of pleuran, an alkali-insoluble β-D-glucan. Carbohydr Polym 24:107–111

Kawagishi H, Inagaki R, Kanao T, Mizuno T, Shimura K, Ito H, Hagiwara T, Hakamura T (1989) Fractionation and antitumor activity of the water-insoluble residue of Agaricus blazei fruiting bodies. Carbohydr Res 186:267–274

Kawagishi H, Kanao T, Inagaki R, Mizuno T, Shimura K, Ito H, Hagiwara T, Hakamura T (1990) Formulation of a potent antitumor (1→6)-beta-D-glucan-protein complex from Agaricus blazei fruiting bodies and antitumor activity of the resulting products. Carbohydr Polym 12:393–404

Kidd PM (2000) The use of mushroom glucans and proteoglycans in cancer treatment. Altern Med Rev 5:4–27

Kiho T, Nagai YS, Sakushima M, Ukai S (1992a) Polysaccharides in fungi: XXIX. Structural features of two antitumor polysaccharides from the fruiting bodies of Armillariella tabescens. Chem Pharm Bull (Tokyo) 40:2212–2214

Kiho T, Shiose Y, Nagai K, Ukai S (1992b) Polysaccharides in fungi: XXX. Antitumor and immunomodulating activities of two polysaccharides from the fruiting bodies of Armillariella tabescens. Chem Pharm Bull (Tokyo) 40:2110–2214

Kiho T, Yoshida I, Katsuragawa M, Sakushima M, Usui S, Ukai S (1994) Polysaccharides in fungi: XXXIV. A polysaccharide from the fruiting bodies of Amanita muscaria and the antitumor activity of its carboxymethylated product. Biol Pharm Bull 17:1460–1462

Kim BK, Choi EC, Chung KS, Kang CY, Kim SH, Kim JS, Kim YJ, Lee KL, Lee JK (1982) The constituents of higher fungi of Korea: antitumor polysaccharides from the carpophores of some Basidiomycetes. Arch Pharmacol Res (Seoul) 5:21–24

Kim HM, Han SB, Oh GT, Kim YH, Hong DH, Hong ND, Yoo ID (1996) Stimulation of humoral and cell mediated immunity by polysaccharide from mushroom Phellinus linteus. Int J Immunopharmacol 18:295–303

Kim YS, Park KS, Park HK, Kim SW (1994) Compositional sugar analysis of polysaccharides by high perfomance liquid chromatography and gas chromatography. Arch Pharmacol Res (Seoul) 17:337–342

Kirk PM, Cannon PF, David JC, Stalpers JA (2001) Ainsworth and Bisby’s dictionary of the fungi, 9th edn. CAB International, Wallingford

Kosuna K (1998) Polysaccharides and preparation thereof. US Patent 5756318, 26 May 1998

Kuniak L, Karácsonyi ˇS, S, Augusti J, Ginterová A, Széchényl ˇKravarik D, Dubaj J, Varjú J (1993) A new fungal glucan and its preparation. World Patent 9312243, 24 June 1993

Liou YF, Lin KH (1979) Preparation of polysaccharides from Fomes japonicus (Fr.) Sacc. – screening for antitumor and cytotoxic substances. Taiwan Yi Xue Hui Za Zhi 78:549–557

Liu F, Ooi VEC, Liu WK, Chang ST (1996) Immunomodulation and antitumor activity of polysaccharide-peptide complex from the culture filtrates of a local edible mushroom, Trichol­oma lobayense. Gen Pharmacol 27:621–624

Lorenzen K, Anke T (1998) Basidiomycetes as a source for new bioactive natural products. Curr Org Chem 2:329–364

Ma Y, Mizuno T, Ito H (1991) Antitumor activity of some polysaccharides isolated from a Chinese mushroom, “Huangmo”, the fruiting body of Hohenbuehelia serotina. Agric Biol Chem 55:2701–2710

Maeda YY, Watanabe ST, Chihara C, Rokutanda M (1988) Denaturation and renaturation of a β-1,6; 1,3-glucan, lentinan, associated with expression of T-cell-mediated responses. Cancer Res 48:671–675

Marchessault RH, Deslandes Y, Ogawa K, Sundarajan PR (1977) X-ray diffraction data for β-D-glucan. Can J Chem 55:300–303

Matsushita K, Kuramitsu Y, Ohiro Y, Obara M, Kobayashi M, Li YQ, Hosokawa M (1998) Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anti Cancer Drugs 9:343–350

Min HK, Choi EC, Kim BK (1980) Studies on the constituents of the higher fungi of Korea: 18. Components of Russula pseudo­delica and Microporus affinis. Korean J Mycol 8:13–20

Misaki A, Nasu M, Sone Y, Kishida E, Kinoshita C (1986) Comparison of structure and antitumor activity of polysaccharides isolated from Fukurotake, the fruiting body of Volvariella vol­vacea. Agric Biol Chem 50:2171–2184

Miyazaki T, Nishijima M (1981) Studies on fungal polysaccharides. XXVII. Structural examination of a water-soluble, antitumor polysaccharide of Ganoderma lucidum. Chem Pharm Bull (Tokyo) 29:3611–3616

Miyazaki T, Yadomae T, Terui T, Yamada H, Kikuchi T (1975) Studies on fungal polysaccharide. XVII. A new glucuronan “protuberic acid” produced by a fungus Kobayasia nipponica. Biochim Biophys Acta 385:345–353

Mizuno M, Shiomi Y, Minato K, Kawakami S, Ashida H, Tsuchida H (2000) Fucogalactan isolated from Sarcodon aspratus elicits release of tumor necrosis factor-alpha and nitric oxide from murine macrophages. Immunopharmacology 46:113–121

Mizuno T (1996) Development of antitumor polysaccharides from mushroom fungi. Foods Food Ingred J Jpn 167:69–85

Mizuno T (1999a) The extraction and development of antitumor-active polysaccharides from medicinal mushrooms in Japan. Int J Med Mushrooms 1:9–29

Mizuno T (1999b) Bioactive substances in Hericium erinaceus (Bull.: Fr.) Pers. (Yamabushitake), and its medicinal utilization. Int J Med Mushrooms 1:105–119

Mizuno T (2000) Development of an antitumor biological response modifier from Phellinus linteus (Berk. et Curt.) Teng (Aphyllophoromycetideae). Int J Med Mushrooms 2:21–33

Mizuno T (2002) Medicinal properties and clinical effects on Agaricus blazei Murr. Int J Med Mushrooms 4:(in press)

Mizuno T, Zhuang C (1995) Maitake, Grifola frondosa: pharmacological effects. Food Rev Int 11:135–149

Mizuno T, Ohsawa K, Hagiwara N, Kuboyama R (1986) Fractionation and characterization of antitumor polysaccharides from Maitake, Grifola frondosa. Agric Biol Chem 50:1679–1688

Mizuno T, Hagiwara T, Nakamura T, Ito H, Shimura K, Sumiya T, Asakura A (1990a) Antitumor activity and some properties of water-soluble polysaccharides from “Himematsutake”, the fruiting body of Agaricus blazei Murrill. Agric Biol Chem 54:2889–2896

Mizuno T, Inagaki R, Kanao T, Hagiwara T, Nakamura T, Ito H, Shimura K, Sumiya T, Asakura A (1990b) Antitumor activity and some properties of water-insoluble hetero-glycans from “Himematsutake”, the fruiting body of Agaricus blazei Murrill. Agric Biol Chem 54:2897–2906

Mizuno T, Ando M, Sugie R, Ito H, Shimura K, Sumiya T, Matsuura A (1992) Antitumor activity of some polysaccharides isolated from an edible mushroom, ningyotake, the fruiting body and the cultured mycelium of Polyporus confluens. Biosci Biotechnol Biochem 56:34–41

Mizuno T, Ma Y, Ito H, Suzuki C (1994) Water insoluble polysaccharide originating in mushroom, its production, and antitumor agent mainly comprising the polysaccharide. Japanese Patent 06–080703, 22 March 1994

Mizuno T, Kinoshita T, Zhuang C, Ito H, Mayuzumi Y (1995a) Antitumor-active heteroglycans from Niohshimeji mushroom, Tricholoma giganteum. Biosci Biotechnol Biochem 59:568–

Mizuno T, Saito H, Nishitoba T, Kawagashi H (1995b) Antitumor-active substances from mushrooms. Food Rev Int 11:23–61

Mizuno T, Yeohlui P, Kinoshita T, Zhuang C, Ito H, Mayuzumi Y (1996) Antitumor activity and chemical modification of polysaccharides from Niohshimeji mushroom, Tricholoma gigant­eum. Biosci Biotechnol Biochem 60:30–33

Mizuno T, Morimoto M, Minato KI, Tsuchida H (1998) Polysaccharides from Agaricus blazei stimulate lymphocyte T-cell subsets in mice. Biosci Biotechnol Biochem 62:434–437

Mizuno T, Zhuang C, Abe K, Okamoto H, Kiho T, Ukai S, Leclerc S, Meijer L (1999a) Antitumor and hypoglycemic activities of polysaccharides from the sclerotia and mycelia of Inonotus obliquus (Pers.: Fr.) Pil. (Aphyllophoromycetideae). Int J Med Mushrooms 1:301–316

Mizuno T, Minato K, Ito H, Kawade M, Terai H, Tsuchida H (1999b) Antitumor polysaccharide from the mycelium of liquid-cultured Agaricus blazei Murrill. Biochem Mol Biol Int 47:707–714

Nakajima K, Hirata Y, Uchida H, Watabe Y, Taniguchi T, Obayashi A, Tanabe O (1980) Polysaccharides having anti-carcinogenic activity and method for producing same. UK Patent 2031446, 23 April 1980

Nakashima S, Umeda Y, Kanada T (1979) Effect of polysaccharides from Ganoderma applanatum on immune response. I. Enhancing effect on the induction of delayed hypersensitivity in mice. Microbiol Immunol 23:501–513

Nakayoshi H, Watanebe T, Yamamura Y, Ono M (1968) Suppression of Sarcoma 37 in mice by the treatment with extracellular polysaccharide produced by a strain of Crepidotus sp. Jpn J Exp Med 38:437–442

Nanba H (1998) Proteoglycan and antidiabetic drug. Japanese Patent 10–182702, 7 July 1998

Nanba H, Hamaguchi A, Kuroda H (1987) The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola fron­dosa (Maitake). Chem Pharm Bull (Tokyo) 35:1162–1168

Ohno N, Iino K, Takeyama T, Suzuki I, Sato K, Oikawa S, Miyazaki T, Yadomae T (1985) Structural characterization and antitumor activity of the extracts from matted mycelium of cultured Grifola frondosa. Chem Pharm Bull (Tokyo) 33:3395– 3401

Ohno N, Adachi Y, Suzuki I, Sato K, Oikawa S, Yadomae T (1986) Characterization of the antitumor glucan obtained from liquid-cultured Grifola frondosa. Chem Pharm Bull (Tokyo) 34:1709–1715

Ohno N, Miura NN, Nakajima M, Yadomae T (2000) Antitumor 1,3-beta-glucan from cultured fruit body of Sparassis crispa. Biol Pharm Bull 23:866–872

Ohtsuka S, Ueno S, Yoshikumi C, Hirose F, Ohmura Y, Wada T, Fujii T, Takahashi E (1973) Polysaccharides having an anticarcinogenic effect and a method of producing them from species of Basidiomycetes. UK Patent 1331513, 26 September 1973

Ohtsuka S, Ueno S, Yoshikumi C, Hirose F, Ohmura Y, Wada T, Fujii T, Takahashi E (1977) Polysaccharides and method for producing same. US Patent 4051314, 27 September 1977

Okamura K, Suzuki M, Chihara T, Fujiwara A, Fukuda T, Goto S, Ichinohe K, Jimi S, Kasamatsu T (1986) Clinical evaluation of schizophyllan. Cancer 58:865–872

Ooi VEC, Liu F (1999) A review of pharmacological activities of mushroom polysaccharides. Int J Med Mushrooms 1:195– 206

Paulik S,ˇˇcec, Mojiˇsová J, ˇSvrˇDurove A, Beniˇsek Z, Húska M (1996) The immunomodulatory effect of the soluble fungal glucan (Pleurotus ostreatus) on delayed hypersensitivity and phagocytic ability of blood leucocytes in mice. J Vet Med B 43:129–135

Reshetnikov SV, Wasser SP, Tan KK (2001) Higher Basidiomycota as a source of antitumor and immunostimulating polysaccharides. Int J Med Mushrooms 3:361–394

Saito K, Nishijima M, Miyazaki T (1989) Studies on fungal polysaccharides: XXXV. Structural analysis of an acidic polysaccharide from Ganoderma lucidum. Chem Pharm Bull (Tokyo) 37:3134–3136

Schaeffer DJ, Krylov VS (2000) Anti-HIV activity of extracts and compounds from algae and Cyanobacteria. Ecotoxicol Environ Saf 45:208–227

Sharon N, Lis H (1993) Carbohydrates in cell recognition. Sci Am Jan:74–81

Song CH, Jeon YJ, Yang BK, Ra KS, Kim HI (1998) Anti-complementary activity of endopolymers produced from submerged mycelial culture of higher fungi with particular reference to Lentinus edodes. Biotechnol Lett 20:741–744

Sugimachi K, Maechara Y, Ogawa M, Kakegawa T, Tomira M (1997) Dose intensity of uracil and tegafur in postoperative chemotherapy for patients with poorly differentiated gastric cancer. Cancer Chemother Pharmacol 40:233–238

Stamets P (2000) Growing gourmet and medicinal mushrooms, 3rd edn. Ten Speed Press, Berkeley, Calif.

Tsuchida H, Mizuno M, Taniguchi Y, Ito H, Kawade M, Akasaka K (2001) Glucomannan separated from Agaricus blazei mushroom culture and antitumor agent containing as active ingredient. Japanese Patent 11–080206, 26 March 2001

Tzianabos AO (2000) Polysaccharide immunomodulators as theurapeutic agents: structural aspects and biological function. Clin Microbiol Rev 13:523–533

Ueno S, Yoshikumi C, Hirose F, Omura Y, Fujii T, Ohara M, Matsunaga K (1978) Preparation of anti-tumor polysaccharides. Japanese Patent 53109915, 26 September 1978

Ukai S, Morisaki S, Goto M, Kiho T, Hara C, Hirose K (1982) Polysaccharides in fungi. VII. Acidic heteroglycans from the fruit bodies of Auricularia auricula-judae Quél. Chem Pharm Bull 30:635–643

Ukai S, Kiho T, Hara C, Morita M, Goto A, Imaizumi N, Hasegawa Y (1983) Polysaccharides in fungi: XIII. Antitumor activity of various polysaccharides isolated from Dictyophora indusiata, Ganoderma japonicum, Cordyceps cicadae, Auri­cularia auricula-judae and Auricularia sp. Chem Pharma Bull (Tokyo) 31:741–744

Ukawa Y, Ito H, Hisamatsu M (2000) Antitumor effects of (1→3)beta-D-glucan and (1→6)-beta-D-glucan purified from newly cultivated mushroom, Hatakeshimeji (Lyophyllum decastes Sing.). J Biosci Bioeng 90:98–104

Wang G, Zhang J, Mizuno T, Zhuang C, Ito H, Mayuzumi H, Okamoto H, Li J (1993) Antitumor active polysaccharides from the Chinese mushroom Songshan Lingzhi, the fruiting body of Ganoderma tsugae. Biosci Biotechnol Biochem 57:894–900

Wang HX, Ng TB, Ooi VEC, Liu WK, Chanf ST (1996) A polysaccharide-peptide complex from culture mycelia of the mushroom Tricholoma mongolicum with immunoenhancing and antitumor activities. Biochem Cell Biol 74:95–100

Wasser SP, Weis AL (1997a) Shiitake mushrooms [Lentinus edodes (Berk.)Sing.]. In: Nevo E (ed) Medicinal mushrooms. Peledfus, Haifa, Israel

Wasser SP, Weis AL (1997b) Reishi mushroom [Ganoderma lucidum (Curt.: Fr.)P.Karst.]. In: Nevo E (ed) Medicinal mushrooms. Peledfus, Haifa, Israel

Wasser SP, Weis AL (1999) Medicinal properties of substances occurring in Higher Basidiomycetes mushrooms: current perspectives. Int J Med Mushrooms 1:31–62

Wasser SP, Nevo E, Sokolov D, Reshetnikov SV, Timor-Tismenetsky M (2000) Dietary supplements from medicinal mushrooms: diversity of types and variety of regulations. Int J Med Mushrooms 2:1–19

Wasser SP, Didukh MY, Meijer A de, Amazonas MALL de, Nevo E, Stamets P (2002) Is widely cultivated culinary-medicinal mushroom indeed Agaricus blazei Murrill? Int J Med Mushrooms 4 (in press)

Yadomae T (2000) Structure and biological activities of fungal β-1,3-glucans. Yakugaku Zasshi 120:413–431

Yadomae T, Ohno N (2000) Sparassis crispa Fr. extract. Japanese Patent 2000–217543, 8 August 2000

Yanaki T, Ito W, Tabata K, Kojima T, Norizuye T, Takano N, Fujita H (1983) Correlation between the antitumor activity of a polysaccharide schizophyllan and its triple-helical conformation in dilute aqueous solution. Biophys Chem 17:337– 342

Yanaki T, Ito W, Tabata K (1986) Correlation between antitumor activity of schizophyllan and its triple helix. Agric Biol Chem 509:2415–2416

Ying J, Mao X, Ma Q, Zong Y, Wen H (1987) Icons of medicinal fungi from China (translated, Yuehan X). Science Press, Beijing

Yoshida I, Kiho T, Usui S, Sakushima M, Ukai S (1996) Polysaccharides in fungi. XXXVII. Immunomodulating activities of carboxymethylated derivatives of linear (1→3)-alpha-D-glucans extracted from the fruiting bodies of Agrocybe cylindra­cea and Amanita muscaria. Biol Pharm Bull 19:114–121

Yoshioka Y, Ikekawa T, Nida M, Fukuoka F (1972) Studies on antitumor activity of some fractions from basidiomyces. I. An antitumor acidic polysaccharide fraction of P. ostreatus (Fr.) Quél. Chem Pharm Bull (Tokyo) 20:1175–1180

Yui T, Ogawa K, Kakuta M, Misaki A (1995) Chain conformation of a glucurono-xylo-mannan isolated from fruit body of Trem­ella fuciformis Berk. J Carbohydr Chem 14:255–263

Zhang J, Wang G, Li H, Zhuang C, Mizuno T, Ito H, Suzuki C, Okamoto H, Li J (1994a) Antitumor polysaccharides from Chinese mushroom, “Yuhuahgmo”, the fruiting body of Pleurotus citrinopileatus. Biosci Biotechnol Biochem 58:1195– 1201

Zhang J, Wang G, Li H, Zhuang C, Mizuno T, Ito H, Mayuzumi H, Okamoto H, Li J (1994b) Antitumor active protein-containing glycans from the Chinese mushroom Songshan Lingzhi, Gano­derma tsugae mycelium. Biosci Biotechnol Biochem 58:1202– 1205

Zhang QH, Lin ZB (1999) The antitumor activity of Ganoderma lucidum (Curt.: Fr.) P.Karst. (Ling Zhi) (Aphyllophoromycetideae) polysaccharides. Int J Med Mushrooms 1:207–215

Zhu D (1987) Recent advances on the active components in Chinese medicines. Abstr Chin Med 1:251–286

Zhuang C, Mizuno T, Shimada A, Ito H, Suzuki C, Mayuzumi Y, Okamoto H, Ma Y, Li J (1993) Antitumor protein-containing polysaccharides from a Chinese mushroom Fengweigu or Houbitake, Pleurotus sajor-caju (Fr.) Sing. Biosci Biotechnol Biochem 57:901–906

Zhuang C, Mizuno T, Ito H, Shimura K, Sumiya T, Kawade M (1994a) Antitumor activity and immunological property of polysaccharides from the mycelium of liquid-cultured Grifola frondosa. Nippon Shokuhin Kogyo Gakkaishi 41:724– 732

Zhuang C, Mizuno T, Ito H, Shimura K, Sumiya T (1994b) Chemical modification and antitumor activity of polysaccharides from the mycelium of liquid-cultured Grifola frondosa. Nippon Shokuhin Kogyo Gakkaishi 41:733–740

1 S.P. Wasser

Institute of Evolution, University of Haifa,

Mt. Carmel, Haifa 31905, Israel
e-mail: spwasser@research.haifa.ac.il
Tel.: +972-4-8249218, Fax: +972-4-8288197N.G. Kholodny Institute of Botany,
National Academy of Sciences of Ukraine,
Tereshchenkivska str. 2, Kiev 01001, Ukraine

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