Диетичният прием на Витамин K2 (Menaquinone) намалява риска от коронарна болест на сърцето: Ротердамското проучване



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TABLE 4

Връзка между приема на менаквинон и калцирането на аортата

при 4473 холандски мъже и жени на и над 55 години1,2





Енергийно коригиран прием на менаквинон (μg/ден)




<21.6

21.6-32.7




>32.7




P за тенденция

n

1468

1493




1512







Среден прием, μg/ден

15.1

26.9




40.9







Умерено калциране



















Контроли, n

916

958




1000







Случаи, n

454

452




453







OR, модел13

1

0.93 (0.79, 1.10)




0.94 (0.80, 1.11)




0.49

OR, модел 24

1

0.91 (0.77, 1.09)




0.93 (0.76, 1.12)




0.45

Тежко калциране



















Контроли, n

916

958




1000







Случаи, n

98

83




59







OR, модел1

1

0.75 (0.54, 1.03)




0.56 (0.39, 0.80)




0.001

OR, модел 2

1

0.71 (0.50, 1.00)




0.48 (0.32, 0.71)




<0.001

1 Калцирането на аортата бе градирано според дължината на калцираното място т.е.., не/ умерено (референтно) <1 cm; moderate, >1 and <5 cm; severe,

тежко ≥5 cm.

2 OR определено чрез мултивариационна логистична регресия, с 95% CI в скоби и P за линеарна тенденция в тертилите.

3 Моделът включва възраст, пол и общ енергиен прием

4 Моделът включва възраст, пол, общ енергиен прием, BMI, пушене, пакети цигари годишно, диабет, образование (3 категории) и прием на алкохол, SFA, PUFA, флавиноли (quercetin, myricetin, иkaempferol) и калций.







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